The Island of Dr Moreau from the 70's (?) is awesome (well, maybe not awesome, but good anyway). The more recent version with Val Kilmer is total and utter crap, mainly IMHO because Marlon Brando has become a fat, stupid, contemptible, arrogant bastard!
The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. ... The piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the light into the peace and safety of a new dark age.
~ Howard Phillips Lovecraft