It depends on whether it refers to one bloodline or multiple bloodlines. It it is uncertain or ambiguous, I'd have to go with the plural.
The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. ... The piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the light into the peace and safety of a new dark age.
~ Howard Phillips Lovecraft